1 Recruiting
A Prospective Study for the Assessment of Recurrence Risk in Stage II Colon Cancer Patients Using ColoPrint
Condition: Colon Cancer
Intervention:
2 Completed
Mangafodipir as an Adjunct to FOLFOX6 Chemotherapy in Colon Cancer Stage Dukes’ C
Conditions: Chemotherapy; Colon Cancer
Interventions: Drug: Mangafodipir; Drug: Placebo treatment (0.9% NaCl)
3 Completed
MOSAIC – Multicenter International Study of Oxaliplatin/ 5FU-LV in the Adjuvant Treatment of Colon Cancer
Condition: Colonic Neoplasms
Intervention: Drug: Oxaliplatin (SR96669)
4 Completed
Safety Study of 90Y-hMN14 to Treat Colorectal Cancer
Conditions: Colorectal Cancer; Colon Cancer; Rectal Cancer; Colorectal Neoplasms; Colorectal Carcinoma; Colorectal Tumor
Intervention: Drug: hMN14 (labetuzumab)
5 Active, not recruiting
Surgery With or Without Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer
Conditions: Colorectal Cancer; Metastatic Cancer
Interventions: Drug: FOLFOX regimen; Drug: fluorouracil; Drug: leucovorin calcium; Drug: oxaliplatin; Procedure: adjuvant therapy; Procedure: conventional surgery; Procedure: neoadjuvant therapy
6 Completed
Microarray Analysis for Human Genetic Disease
Conditions: Breast Neoplasm; Hereditary Neoplastic Syndrome; Melanoma; Ovarian Neoplasm
Intervention:
7 Completed
Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer
Conditions: Colorectal Neoplasms; Colonic Neoplasms; Rectal Neoplasms
Intervention: Drug: Vatalanib
8 Recruiting
ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Subjects With KRAS Wild-Type Metastatic Colorectal Cancer
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab (Erbitux); Drug: Panitumumab (Vectibix)
9 Completed
Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.
Conditions: Colorectal Neoplasms; Colonic Neoplasms; Rectal Neoplasms
Intervention: Drug: Vatalanib
10 Active, not recruiting
Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer
Conditions: Colorectal Cancer; Metastatic Cancer
Interventions: Biological: bevacizumab; Drug: FOLFOX regimen; Drug: fluorouracil; Drug: leucovorin calcium; Drug: oxaliplatin; Procedure: conventional surgery; Procedure: radiofrequency ablation
11 Completed
Preoperative NSAID to Colorectal Cancer Patients
Condition: Colorectal Cancer
Intervention: Drug: Indomethacin, celecoxib, esomeprazole
12 Recruiting
Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.
Condition: Patients With Previously Untreated Cancer in Colon or Rectum
Interventions: Drug: bevacizumab, erlotinib; Drug: bevacizumab; Drug: low dose capecitabine
13 Completed
Enzastaurin for Patients With Metastatic Colorectal Cancer
Condition: Colonic Neoplasms
Intervention: Drug: Enzastaurin HCl
14 Active, not recruiting
A Study to Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer
Condition: Colorectal Cancer
Interventions: Drug: lenalidomide, cetuximab; Drug: lenalidomide
15 Active, not recruiting
A Study to Evaluate the Efficacy of Bevacizumab in Combination With Tarceva for Advanced Non-Small Cell Lung Cancer
Condition: Non-Small Cell Lung Cancer
Interventions: Drug: bevacizumab; Drug: erlotinib HCl; Drug: placebo
16 Completed
Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL)
Condition: Osteoporosis
Interventions: Drug: lasofoxifene; Other: placebo
17 Completed
Study of Capecitabine and Oxaliplatin in Combination With Radiotherapy in Patients With Unresectable Gastro-Intestinal Cancer
Conditions: Stomach Cancer; Gall Bladder Cancer; Bile Ductus Cancer; Pancreas Cancer; Colorectal Cancer
Intervention: Other: oxaliplatin, capecitabine, radiotherapy
18 Recruiting
Treatment Strategies for Primarily Generalized Colorectal Cancer
Condition: Colorectal Cancer
Intervention: Procedure: Chemotherapy and surgery
19 Active, not recruiting
Oxaliplatin, Capecitabine, and Radiation Therapy With or Without Cetuximab in Treating Patients Undergoing Surgery for High-Risk Rectal Cancer
Condition: Colorectal Cancer
Interventions: Biological: cetuximab; Drug: capecitabine; Drug: oxaliplatin; Procedure: adjuvant therapy; Procedure: conventional surgery; Procedure: neoadjuvant therapy; Radiation: radiation therapy
20 Recruiting
The Northern-European Initiative on Colorectal Cancer
Condition: Colorectal Cancer
Intervention: Procedure: Colonoscopy
21 Active, not recruiting
Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in theTreatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen
Conditions: Colorectal Neoplasms; Neoplasm Metastasis
Interventions: Drug: Aflibercept (AVE0005); Drug: Placebo
22 Active, not recruiting
Cetuximab Combined With Irinotecan in First-Line Therapy for Metastatic Colorectal Cancer (CRYSTAL)
Condition: EGFR-Expressing Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab, 5-Fluorouracil, Folinic acid, Irinotecan; Drug: 5-Fluorouracil, Folinic acid, Irinotecan
23 Completed
A Study of Xeloda (Capecitabine) as a First-Line Therapy in Patients With Metastatic Colorectal Cancer
Condition: Colorectal Cancer
Interventions: Drug: capecitabine [Xeloda]; Drug: Oxaliplatin; Drug: Leucovorin; Drug: 5 FU; Drug: Avastin
24 Active, not recruiting
XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer
Condition: C04.588.274.476.411.307
Interventions: Drug: Oxaliplatin (Eloxatin); Drug: Capecitabine (Xeloda)
25 Active, not recruiting
Panitumumab Plus FOLFIRI in First-line Treatment of Metastatic Colorectal Cancer
Condition: Metastatic Colorectal Cancer
Intervention: Drug: panitumumab and FOLFIRI
26 Active, not recruiting
Comparison of Treatment Effect of Chemotherapy With Panitumumab to Chemotherapy Alone
Condition: Metastatic Colorectal Cancer
Interventions: Drug: FOLFIRI; Drug: Panitumumab
27 Completed
Study Of FOLFIRI Chemotherapy With Or Without Sunitinib In Patients With Metastatic Colorectal Cancer
Condition: Colorectal Neoplasms
Interventions: Drug: 5 fluorouracil; Drug: irinotecan; Drug: levo- leucovorin; Drug: sunitinib; Drug: placebo
28 Recruiting
Phase I/II Combination With Irinotecan- Erbitux
Condition: Metastatic Colorectal Cancer (MCRC)
Interventions: Drug: Cetuximab; Drug: Irinotecan; Drug: Brivanib; Drug: Brivanib Placebo
29 Active, not recruiting
Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases
Conditions: Liver Metastases; Colorectal Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local
Interventions: Drug: Talaporfin sodium; Procedure: Percutaneous placement of device in liver metastases; Device: Interstitial light emitting diodes; Drug: FOLFOX4 OR FOLFIRI regimen
30 Recruiting
FLOX + Cetuximab (Erbitux®) for Patients With Metastatic Colorectal Cancer and Wild Type K-RAS Tumor
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Cetuximab (Erbitux); Drug: Oxaliplatin (Eloxatin) + Fluorouracil + folinic acid
31 Recruiting
Health Economic Evaluation of Primovist-enhanced Liver MRI
Conditions: Colorectal Neoplasms; Neoplasm Metastasis
Interventions: Procedure: Primovist MRI; Procedure: Extracellular contrast media (ECCM) MRI; Procedure: Contrast-enhanced CT
32 Recruiting
Safety Study of DNA Vaccine Delivered by Intradermal Electroporation to Treat Colorectal Cancer
Condition: Colorectal Cancer
Interventions: Biological: tetwtCEA DNA (wt CEA with tetanus toxoid Th epitope); Device: Derma Vax (electroporation device); Biological: GM-CSF; Drug: Cyclophosphamide
33 Completed
Study of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal Cancer
Condition: Colorectal Cancer
Interventions: Drug: cetuximab; Drug: Irinotecan
34 Completed
Has Results
Comparing Irinotecan and 5 FU/FA To 5-FU/FA After Resection Of Liver Metastases For Colorectal Cancer
Conditions: Colorectal Neoplasms; Liver Neoplasms
Interventions: Drug: Irinotecan + 5 FU + folinic acid; Drug: Folinic Acid + 5 FU
35 Active, not recruiting
A Study of Avastin (Bevacizumab) Plus Crossover Fluoropyrimidine-Based Chemotherapy in Patients With Metastatic Colorectal Cancer.
Condition: Colorectal Cancer
Interventions: Drug: bevacizumab [Avastin]; Drug: AIO-IRI, FOLFIRI, CAPIRI or XELIRI; Drug: FUFOX, FOLFOX, CAPOX or XELOX
36 Recruiting
Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)
Condition: Adenomatous Polyposis Coli
Interventions: Drug: Celecoxib; Drug: Placebo
37 Active, not recruiting
Chemotherapy and Avastin Followed by Maintenance Treatment With Avastin +/- Tarceva
Condition: Metastatic Colorectal Cancer
Interventions: Drug: erlotinib (Tarceva); Drug: bevacizumab (Avastin)
38 Recruiting
Radiofrequency Ablation Versus Stereotactic Radiotherapy in Colorectal Liver Metastases
Conditions: Colorectal Carcinoma; Liver Metastases; Efficacy; Toxicity
Intervention: Procedure: SBRT or RFA